Molecular imaging is an exciting and rapidly expanding field that is yielding major scientific and medical breakthroughs. At the heart of the field is research and development into the chemistry and chemical biology of medical isotopes and molecular imaging probes.
In the Valliant group we seek to develop new synthetic methods and technology-based platforms that facilitate the preparation and discovery of novel molecular imaging probes. Our work includes innovations in coordination chemistry, organic synthesis and in chemical biology to create agents that have high affinity for proteins specifically associated with diseases like cancer.
Molecular imaging methods use probes – molecules that seek out the disease markers and that emit a signal that can be detected by an imaging device:
To create new molecular imaging probes requires new chemistry:
- Bioinorganic Chemistry – the chemistry of radiometals and new ligands
- Medicinal Chemistry – new synthetic methods and discovery strategies to prepare molecular imaging probes
- Bioconjugate Chemistry – new ways to link medical isotopes to targeting vectors